Artio Medical announced today it has completed enrolment in its first-in-human study evaluating the Amplifi vein dilation system. In the study, five patients were treated by Adrian Ebner, head of the Cardiovascular Department at Sanatorio Italiano Hospital in Asunción, Paraguay. "I am very...
Hancock Jaffe Laboratories today announced that the US Food and Drug Administration (FDA) has granted Breakthrough Device designation status to the VenoValve, the company’s lead product, which is currently set to begin its US pivotal trial. The VenoValve is a...
A large, single-centre retrospective study has revealed the risk of acute kidney injury (AKI) following pharmacomechanical thrombolysis (PMT) for lower extremity deep vein thrombosis (DVT) is as high as 22%. PMT is an established treatment for selected patients with...
This advertorial, sponsored by BD, is only available in selected countries and geographies. In this case report for Venous News, experts outline the importance of recognising chronic venous obstruction as a crucial contributor to non-healing wounds in patients firstly...
Royal Philips today announced the US Food and Drug Administration (FDA) has granted Breakthrough Device designation for a laser-assisted inferior vena cava (IVC) filter removal device. The proposed device is intended for ablating tissue to remove an IVC filter...
This advertorial, sponsored by BD, is only available in selected countries and geographies. A downloadable version of this advertorial can be found here. In this case report for Venous News, experts outline the importance of recognising chronic venous obstruction as...
 Rachael Morris (London, UK) talks to Venous News about VEINES QoL/Sym—a venous disease-specific quality of life (QoL) questionnaire for patients with chronic venous insufficiency—as well as the findings of a study which sought to evaluate changes in venous-specific QoL...
Transluminal injection of foam sclerotherapy (TLFS) combined with endovenous laser ablation (EVLA) is a safe and feasible procedure that improves venous clinical severity score (VCSS) and reduces additional second-stage interventions compared to ultrasound-guided foam sclerotherapy (UGFS) combined with EVLA....
Based on findings presented at the 21st European Venous Forum (EVF) Annual Meeting (24–26 June, online), Imre Bihari (A+B Clinic, Budapest, Hungary) speaks to Venous News about the benefits of laser crossectomy. What is the laser crossectomy technique used for...
Viz.ai has partnered with Avicenna.AI to enable intelligent care coordination and improve patient triage of patients suffering from pulmonary embolism (PE) and aortic disease. Avicenna.AI’s US Food and Drug Administration (FDA)-approved algorithms for PE and type A and type B aortic...
Fist Assist Devices has announced a two-year affiliation with Airos Medical to commercialise and launch sales of the Fist Assist FA-1 device in the USA. The Fist Assist FA-1 is a wearable, patent-protected, intermittent compression device that recently received...
Surmodics recently announced that it has acquired privately-held Vetex Medical Limited. The Galway, Ireland-based medical device developer and manufacturer has focused exclusively on venous clot removal solutions. The transaction expands Surmodics’ thrombectomy portfolio with a second US Food and...
Despite a high rate of initial anticoagulation, patients with isolated superficial vein thrombosis (SVT) are at risk of thromboembolic complications—including recurrent or extended SVT and recurrent venous thromboembolism (VTE)—at three-month follow-up. This is according to the INSIGHTS-SVT (Investigating significant...
Venous disease-specific quality of life (QoL), as measured by the VEINES (Venous insufficiency epidemiological and economic study)-QoL/Sym, improves significantly after iliac vein stenting for chronic venous obstruction. This is according to the 2021 European Venous Forum (EVF) Prize-winning paper...
The US Food and Drug Administration (FDA) has enhanced the indications for use of the Bashir endovascular catheter (Thrombolex) and the Bashir Plus endovascular catheters (Bashir+10, Bashir+20, Bashir+30, Bashir+40; Thrombolex). These catheters are intended for the controlled and selective...
The Janssen Pharmaceutical Companies of Johnson & Johnson recently announced it has submitted a new drug application (NDA) to the US Food and Drug Administration (FDA) for the use of Xarelto (rivaroxaban) in paediatric patients. The NDA seeks two...
Fist Assist Devices has received US Food and Drug Administration (FDA) 510(k) clearance for use of the Fist Assist FA-1 device in the USA as an arm massage and increased vein circulation device, and has commenced marketing the Fist...
Venous stenting can have myriad benefits for carefully selected patients with deep and pelvic venous disease. However, as venous stenting has quickly gained popularity, concerns have arisen about the appropriateness of its use and the potential complications that may occur. Rick...
Among patients with a Caprini score of ≥11 who received standard prophylaxis for venous thromboembolism (VTE), adjunctive intermittent pneumatic compression (IPC) resulted in a significantly lower incidence of asymptomatic venous thrombosis. This is according to the findings of the...
A study by Mayo Clinic researchers provides some clarity on the use of direct oral anticoagulants (DOACs), such as apixaban and rivaroxaban, to treat acute venous thromboembolism (VTE) in patients with gastrointestinal cancers. The findings were published 2 June...
Inari Medical today announced "strongly positive" interim results from the first 250 deep vein thrombosis (DVT) patients enrolled in the CLOUT (ClotTriever outcomes) registry. These latest data showed that the ClotTriever system removed 100% of the blood clots in...
A study suggests avoiding propofol for intraprocedural sedation during catheter-directed interventions (CDIs) for intermediate-risk pulmonary embolism (PE) because it can have detrimental effects. Propofol is the most commonly used parenteral anaesthetic agent in the USA, extensively used for minor...
Medical imaging artificial intelligence (AI) specialist Avicenna.AI recently announced that it has received certification in the USA and European Union (EU) for CINA CHEST, its new AI solution that leverages deep learning algorithms for emergency triage of deadly vascular...
Monroe Carell Jr Children's Hospital at Vanderbilt (Nashville, USA) has launched a study to determine the impact of a predictive model for identifying paediatric patients at risk for developing venous thromboembolism (VTE). The study uses advanced predictive analytics to inform...
Koya Medical announced today that it has received US Food and Drug Administration (FDA) 510(k) clearance for its active compression therapy system Dayspring for the treatment of lymphoedema and venous diseases that impact lymphatic flow in the lower extremities....
The European Union (EU) Medical Devices Regulation (MDR) takes effect from today (26 May 2021). The Regulation revises quality and safety standards and the range of regulated devices and was first initiated in May 2017, with an initial three-year...
Boston Scientific and BD have both initiated recalls of venous stents. According to a US Food and Drug Administration (FDA) medical device recall notice posted 21 May, Boston Scientific has recalled its Vici venous stent system (Vici SDS) and...
LimFlow SA recently announced the publication of 12-month data from the full patient cohort in its PROMISE I study of the LimFlow percutaneous deep vein arterialisation (pDVA) system in the Journal of Vascular Surgery. Results showed sustained positive outcomes...
Manjit Gohel (Cambridge, UK) and Stephen Black (London, UK) write that several recent advances in the management of venous thromboembolism (VTE) have provided clarity and consensus on this important topic. However, they stress that areas of controversy remain. VTE has...
At VENOUS2021 (17–20 March, virtual), the annual meeting of the American Venous Forum, Geno Merli (Thomas Jefferson University Hospital, Philadelphia, USA) gave a keynote lecture on venous thromboembolism (VTE) in COVID-19 patients, detailing an “acute and extended” risk in...
The publication of positive new data and a need to minimise hospital visits during the COVID-19 pandemic has seen a general trend towards using more direct oral anticoagulants (DOACs), write Ankur Thapar, a consultant vascular surgeon, and Premalatha Sharavanan,...
While various treatment regimens for the “unique complication” of endothermal heat-induced thrombosis (EHIT) following endovenous ablation have been developed, Lowell S Kabnick tells Venous News, none have achieved universal acceptance. That is, he argues, until now. In this article,...
From the first research linking heparin to a reduction in fatal pulmonary embolism (PE), to the development and refinement of risk assessment tools to lower the risk of thrombosis, Joseph Caprini (University of Chicago Pritzker School of Medicine, Chicago,...
Sky Medical Technology has announced the inclusion of its flagship product, the Geko device, on a US Veterans Health Administration (VA) Federal Supply Schedule (FSS) contract awarded to its federal distribution partner, Marathon Medical. The wearable, clinically proven Geko is...
As evolving treatment modalities offer the potential for improved outcomes in patients with deep venous disease, the importance of patient selection and the need for high-volume expert treatment centres to treat these patients were underscored by world-leading experts during...
An international panel of venous and lymphatic experts has called for a multidisciplinary approach to identify the causes of severely swollen lower limbs and to improve the treatment of this common condition, which has been poorly managed all over...
Hancock Jaffe Laboratories has revealed that the United States Patent and Trademark Office (USPTO) has issued the first patent covering the company's VenoValve. The patent is entitled 'Implantable Vein Frame' and is US patent number 10,959,841. The company recently announced...
The results of a two-year study support the continued safety and effectiveness of the Zilver Vena Venous Stent (Cook Medical) in treating symptomatic iliofemoral venous outflow obstruction, according to findings presented at the 2021 meeting of the Society of...
Hancock Jaffe Laboratories recently announced that the US Food and Drug Administration (FDA) has approved the company's Investigational Device Exemption (IDE) application to begin the US pivotal trial for the VenoValve. The VenoValve is an implantable valve designed to...
A recent study on iliac vein stenting showed better short- and mid-term patency rates when intravascular ultrasound (IVUS) was utilised prior to stent deployment in addition to multiplanar venography compared to venography alone. The data were presented at VENOUS2021 (17–20...
According to a recent study, patients with cancer under immune checkpoint inhibitor therapy are at high risk of thromboembolism, especially venous thromboembolism (VTE). Furthermore, VTE occurrence was associated with increased mortality. Florian Moik (Comprehensive Cancer Center of MedUni...
Inari Medical has announced the enrolment of the first high-risk pulmonary embolism (PE) patient in the FLAME (FlowTriever for acute massive pulmonary embolism) study. One in 20 PE diagnoses is categorised as high risk and these are associated with...
Faced with a need to limit hospital visits and conserve personal protective equipment (PPE) in the wake of COVID-19, an 11-centre, hospital-based anticoagulation monitoring service (AMS) in Ohio, USA, needed to adapt fast. Addressing viewers of VENOUS2021 (17–20 March,...
A new review concludes that the implementation of clinical guidelines for the management of patients with deep vein thrombosis (DVT) varies among countries, from strict adherence to no adherence at all. “In this content,” suggest authors Carla Rognoni (SDA...
LimFlow announced today that the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) has approved its Clinical Trial Notification (CTN) for the Japanese cohort of the ongoing PROMISE II pivotal trial of the LimFlow percutaneous deep vein arterialisation (pDVA) system.  PROMISE...
Long-term results of patients who underwent outpatient laser treatment for varicose veins at the great saphenous vein (GSV) or small saphenous vein (SSV) in 2008–2009 have been published in the Journal of Vascular Surgery: Venous and Lymphatic Disorders. The...
Vetex Medical has announced positive one-year outcomes from a European clinical study of the ReVene thrombectomy catheter. In patients with iliofemoral vein thrombus, the device was found to significantly improve symptoms and quality of life, while reducing leg swelling....
A new study has found that patients who require recanalisation of a completely occluded venous outflow tract before stenting have a high rate of early reocclusion. Writing in the Journal of Vascular Surgery: Venous and Lymphatic Disorders, William A...
According to a recent study, longer segments of great saphenous vein (GSV) reflux appear to correlate with symptom severity. In addition, researchers noted a small to moderate correlation between length of GSV segment ablated and symptom improvement, which they...
Lowell Kabnick (Lake Worth, USA) talks to Venous News ahead of this year’s Charing Cross Symposium (CX), which is being held online 19–22 April. In 2021, the conference will focus on controversies within the vascular and endovascular space. Kabnick discusses...
Vetex Medical has announced US Food and Drug Administration (FDA) 510(k) clearance for the ReVene thrombectomy catheter. ReVene uses dual-action technology designed to de-clot peripheral vessels, such as in deep vein thrombosis (DVT), through wall-to-wall contact in a single...
In a comparison of two clinical scales that assess quality of life (QoL) in post-thrombotic syndrome, Angela Lee (McGill University, Montreal, Canada) and colleagues conclude that, when a single scale is used for this purpose, the Villalta scale will...
In a recent meta-analysis, Yang Liu, Huan Lu (Henan Cancer Hospital, Zhengzhou, China), and colleagues found insufficient evidence to prove that inferior vena cava (IVC) filters can reduce pulmonary embolism (PE)-related mortality and overall mortality. However, they did find...
Results of a first-in-human study to assess the safety and feasibility of the Bashir endovascular catheter (Thrombolex) for the treatment of acute intermediate-risk pulmonary embolism (PE) have been published in Circulation: Cardiovascular Interventions. Authors Akhilesh Sista (New York University...
The first patient has been enrolled in a postmarket clinical follow-up (PMCF) study of the BeYond venous self-expanding stent system (Bentley), a press release states. The stent was launched in a selection of venous centres across Europe in late 2020. Michael...
Hancock Jaffe Laboratories recently announced that it has completed a public offering of its securities, generating approximately US$41.4 million of gross proceeds, prior to deducting underwriting discounts and commissions, and expenses. Proceeds from the offering will be used for...
Society for Vascular Surgery (SVS) Vascular Quality Initiative (VQI) venous case volume and registry data entry was “sharply reduced” during the initial phase of the COVID-19 pandemic, a retrospective review has concluded. Findings were published online in the Journal...
Outcomes of the COMETA (Compression following endothermal ablation) study were published in the February edition of Annals of Surgery. The results suggest that wearing compression stockings after endothermal ablation is “advantageous in the first few days after treatment” and...
Bayer has received approval in the UK for the use of its oral Factor Xa inhibitor Xarelto (rivaroxaban) to treat venous thromboembolism (VTE) and to prevent VTE recurrence in children from birth to below 18 years after at least...
Michael Lichtenberg (Karolinen Hospital, Arnsberg, Germany) details three-year data from the Arnsberg venous registry on the VICI Venous Stent System (Boston Scientific). This video forms part of a digital advertorial sponsored by Boston Scientific.
This advertorial is sponsored by Boston Scientific. The VICI Venous Stent System (Boston Scientific) is associated with excellent primary patency rates, with concomitant symptomatic improvement in Clinical-Etiological-Anatomical-Pathophysiological (CEAP) classification, directly after stenting and in long-term follow-up out to 36 months....
The VICI Venous Stent System (Boston Scientific) is associated with excellent primary patency rates, with concomitant symptomatic improvement in Clinical-Etiological-Anatomical-Pathophysiological (CEAP) classification, directly after stenting and in long-term follow-up out to 36 months. This is the headline finding of...
“I consider intravascular ultrasound (IVUS) to be essential equipment in venous interventions,” Rick de Graaf (Clinic of Friedrichshafen, Friedrichshafen, Germany) told viewers of LINC 2021 (The Leipzig Interventional Course; 25–29 January, online). De Graaf was speaking during a session...
Control Medical Technology recently announced that their US Food and Drug Administration (FDA)-cleared Control 11F mechanical thrombectomy system has been used to remove large blood clots from patients with deep vein thrombosis (DVT). “The Control 11 French mechanical thrombectomy system...
A large, prospective, single-centre, randomised trial from Spain comparing two open surgical techniques with radiofrequency ablation (RFA) to treat saphenous incompetence found RFA comparable to both invasive approaches in terms of clinical recurrence and quality of life at two...
Inari Medical has announced strongly positive interim results of the first 64 chronic deep vein thrombosis (DVT) patients enrolled in the ClotTriever outcomes (CLOUT) registry. The subanalysis, which focused on patients with an estimated clot age over six weeks,...
Venous thromboembolism (VTE) in COVID-19 patients was a key topic on the agenda of The VEINS (Venous Endovascular INterventional Strategies) session at VIVA 2020 (Vascular InterVentional Advances; 14–15 November, virtual). Based on emerging data and guidelines, Yogen Kanthi (National...
The nature of venous thromboembolism (VTE) in COVID-19 patients is complex, and treatment strategies regarding drug type and dosing continue to evolve, writes Sanjum Sethi. In this context, Sethi concludes that a multidisciplinary approach to treatment, in the form...
Describing the Northwell CORE-19 registry as “the largest prospective registry of thromboembolic complications in hospitalised COVID-19 patients in the post-hospital discharge period,” lead investigator Alex Spyropoulos (Northwell Health and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New...
The European Society for Vascular Surgery (ESVS) has produced a clinical practice guidelines document on the management of venous thrombosis—the first guidelines the society have produced on this topic. The document was published as an Editor’s Choice paper in...
Results from the EXTRACT-PE trial, which found that Penumbra’s Indigo aspiration system met its predefined safety and efficacy endpoints for the treatment of pulmonary embolism (PE), have been published in JACC: Cardiovascular Interventions. Penumbra’s Indigo system is designed to remove...
A recent randomised controlled trial shows a potential role for higher density types of thermal water in lower limb volume control and quality of life improvement. Investigators Erica Menegatti (University of Ferrara, Ferrara, Italy) and colleagues write in an...
In this article for Venous News, Stephen A Black discusses innovation in the field of thrombolytic-free thrombectomy. He considers "exciting" new developments in mechanical-only approaches and concludes that, "We are making progress on our important objectives as vascular specialists...
The excimer laser sheath technique is safe and effective for removing embedded inferior vena cava (IVC) filters refractory to high-force retrieval, the investigators of a first-in-human escalation trial conclude in the Journal of the American Heart Association (JAHA). “This...
Mahmood Razavi (Orange, USA) speaks to Venous News about the recently initiated VIVID trial – a prospective, multicentre, single-arm study which has just begun enrolment and is designed to evaluate the safety and efficacy of the Vesper DUO Venous Stent System in the...
In a recent randomised controlled trial, an age-adjusted, weight-adjusted dabigatran dosing algorithm was found to be appropriate in children under 18 years old with venous thromboembolism (VTE). Writing in Lancet: Haematology, Jacqueline Halton (University of Ottawa, Ottawa, Canada) and...
In a recent study, factors related with venous thromboembolism (VTE) severity—including pulmonary embolism response team (PERT) referral from the intensive care unit (ICU) and right ventricular dysfunction—and elevated bleeding risk were associated with inferior vena cava (IVC) filter placement...
Aidoc and Imbio have announced a partnership intended to provide an end-to-end artificial intelligence (AI) solution for pulmonary embolism (PE), with the goal of ultimately improving efficiency and quality of PE detection and treatment. "Achieving the value of AI in clinical...
Vesper Medical recently announced initiation of its US Food and Drug Administration (FDA) investigational device exemption (IDE) study—VIVID (Venous stent for the iliofemoral vein investigational clinical trial using the Vesper Duo venous stent system). The VIVID trial is a prospective, multicentre, single-arm...
In a study of interface pressure changes under compression bandages, Junjie Ning, Fedor Lurie (both Jobst Vascular Institute, Toledo, USA), and colleagues found that while pressure decreased over time under all studied bandages, the temporal pattern of pressure change...
Cook Medical has announced that their Zilver Vena venous self-expanding stent is now commercially available to physicians in the USA. Zilver Vena is a self-expanding stent designed to meet the needs of patients suffering from symptomatic iliofemoral venous outflow obstruction....
Penumbra today announced US Food and Drug Administration (FDA) 510(k) clearance for expanded indication of the latest iteration of the Indigo aspiration system, Lightning 12. As part of the Indigo aspiration system, Lightning 12 (Indigo system CAT 12 aspiration catheter...
Amy Ferris (Geriatric and General Medicine Cardiff, Cardiff, Wales, UK), Keith Harding (Welsh Wound Innovation Centre, Ynysmaerdy, Wales, UK), and colleagues have landed on a “suitable protocol” for measuring serum and wound fluid iron levels in the context of...
Inari Medical has announced follow-up results of the first 230 patients enrolled in its FLASH study. FLASH is a real-world registry to study the FlowTriever system in intermediate- and high-risk pulmonary embolism (PE) patients. A press release reports that...
Anthony Comerota (Alexandria, USA), global principal investigator of the VIVO trial, discusses the highlights of the 12-month results of the VIVO clinical study that were presented at VIVA 2020. While the safety and efficacy of the Zilver Vena stent, which...
Vascular Barcelona Devices (VB Devices) recently announced that its Varixio Pod Air product received CE mark approval as a Class 1s medical device. Varixio is a novel, patent-protected system that automates the preparation of foam for sclerotherapy of varicose...
In September 2020, a consensus document outlining the Venous and Lymphatic Triage and Acuity Scale (VELTAS) was co-published in Phlebology and the Journal of Vascular Surgery: Venous and Lymphatic Disorders. The document, authored by representatives of various international societies,...
LimFlow SA has announced the presentation of one-year data from the full patient cohort in its PROMISE I study of the LimFlow percutaneous deep vein arterialisation system, showing sustained positive outcomes for both amputation-free survival and complete wound healing....
Results of the VIVO clinical study support the safety and effectiveness of Cook Medical's recently FDA-cleared Zilver Vena venous stent for the treatment of symptomatic iliofemoral venous outflow obstruction, Anthony Comerota (Inova Fairfax Hospital, Alexandria, USA) revealed in a...
Catalin Toma (University of Pittsburgh, Pittsburgh, USA) recently presented interim results from the FLASH registry during a late-breaking session at TCT Connect (14–18 October, virtual), the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). FLASH (FlowTriever all-comer registry...
An off-label randomised controlled trial (RCT) has found that an investigational stocking, which has no compression in the foot or heel area, is significantly easier to put on and take off, with no inferiority in oedema prevention, compared with...
Results of the ATLANTIS (Aquatic therapy to lower adverse consequences of venous thrombosis and insufficiency) randomised controlled trial (RCT) show that the addition of aquatic activity to the treatment of patients with advanced chronic venous insufficiency is safe and...
Medtronic today announced it has received US Food and Drug Administration (FDA) approval for the Abre venous self-expanding stent system. This device is indicated for use in the iliofemoral veins in patients with symptomatic iliofemoral venous outflow obstruction. The FDA...
The BASHIR™ Endovascular Catheter offers a safe and easy-to-use platform technology, creating immediate blood flow, accelerating thrombolysis, and dissolving large volumes of thrombus burden. This educational supplement, sponsored by Thrombolex, explores the use of various catheter-directed therapies, including their...
The BAS (British Association of Sclerotherapists) interactive Masterclass Series kicked off on 8 October with three experts from the world of vascular surgery sharing their knowledge of 2020 varicose vein treatments. One of the UK’s most experienced vein experts, Bruce...
Cook Medical today announced that the Zilver Vena received US Food and Drug Administration (FDA) premarket approval (PMA) in the USA. The product is expected to be commercially available to physicians in the USA in Q4 2020. Zilver Vena is...
In a systematic review of the worldwide published data on venous thromboembolism (VTE) in COVID-19 patients, Cihan Ay, Stephan Nopp, and Florian Moik (Medical University of Vienna, Vienna, Austria) provide an in-depth analysis on the risk of VTE in...
Patients with venous thromboembolism (VTE) carry a high risk of recurrence. Accordingly, a 16-year Danish prospective cohort study of nearly 74,000 patients with incident VTE concluded that the risk of recurrence is substantial. Furthermore, the scientists found that the recurrence...
Midterm results from a study of the largest population of patients with no-option chronic limb-threatening ischaemia (CLTI) treated with percutaneous deep vein arterialisation (pDVA) using the LimFlow device show that, in this complex group of patients, this treatment method...
The American Venous Forum (AVF) is to stage a four-part series of educational sessions aimed at residents, fellows, and early-career practitioners in vascular surgery, interventional radiology, and a host of other specialties. The live, virtual course—taking place at 8 pm...
Royal Philips has announced the launch of the QuickClear mechanical thrombectomy system. The single-use system delivers an all-in-one aspiration pump and catheter to remove blood clots from the vessels of the peripheral arterial and venous systems and has received...
To deliver clinical and cost benefits, leg ulcer care pathways should be revised to include early assessment and treatment of superficial venous reflux, researchers behind a recent Journal of the American Medical Association (JAMA) Surgery study suggest. The investigators set...
In a recent nationwide study of observational data from the USA, intracranial haemorrhage (ICH) was found to be rare among deep vein thrombosis (DVT) patients treated with catheter-directed thrombolysis (CDT). The study showed that the incidence of ICH has...
A recent systematic review and meta-analysis compared the outcomes of both concomitant and staged superficial varicose tributary (SVT) interventions as an adjunct to endovenous truncal ablation. While both treatments demonstrated safety and efficacy, improvements in early disease severity and...
The Society of Interventional Radiology (SIR) recently published new clinical practice guidelines that provide evidence-based recommendations on the use of inferior vena cava (IVC) filters to treat venous thromboembolism (VTE). “These guidelines allow physicians treating patients at risk of a...
In a recent analysis of 150 patients with post-thrombotic syndrome included in the Swiss and Arnsberg venous stent registries, braided as compared with laser-cut nitinol stents for common femoral vein obstruction appeared to be associated with favourable primary patency...
A new analysis has found that the incidence of cerebral venous thrombosis (CVT) in the USA is higher than previously reported and has increased over time. According to an American Academy of Neurology press release, the study found the...
Patients with acute pulmonary embolism (PE) can be selected for home management using the sPESI score or the Hestia criteria, according to results of the HOME-PE trial presented in a Hot Line session at the European Society of Cardiology...
The Venovo venous stent system from BD has been revealed as one of the 2020 50th Annual Prix Galien USA award nominees in the "Best Medical Technology" category. The Prix Galien award is among the global health innovation industry's...
A recently-published study concludes that three-dimensional (3D) computed tomography venogram (CTV) enables accurate diagnosis and treatment of patients presenting with symptomatic chronic iliofemoral venous obstruction (CIVO). Writing in the Journal of Vascular Surgery: Venous and Lymphatic Disorders, authors Arjun...
The American Heart Association (AHA) has announced that after nearly a decade of steady decline, the death rate for people with pulmonary embolism (PE) reversed course and began rising over the past decade. The study was recently published online...
Three-year results of a randomised controlled trial reveal that, while mechanochemical ablation (MOCA) is a “feasible treatment option” in an outpatient setting, its technical success rates are inferior compared to endovenous thermal ablation. The findings were recently published online...
Thrombolex has announced that it has enrolled the first patient in its pivotal RESCUE trial for the treatment of patients with acute submassive pulmonary embolism (PE) using the Bashir endovascular catheter, under an Investigational Device Exemption (IDE) from the US...
A recent meta-analysis found that direct oral anticoagulants (DOACs) appear to be a “reasonable alternative” to low molecular weight heparin (LMWH) for the treatment of venous thromboembolism (VTE) in cancer patients. The study appeared online on 25 July in...
A randomised controlled trial has found that clinical and patient-reported outcomes following radiofrequency ablation (RFA) of varicose veins with compression are no better than without compression. Madu Onwudike (Manchester University NHS Foundation Trust, Manchester, UK) and colleagues conducted the...
Venous News takes a look back at VIVA 2019 (Vascular InterVentional Advances; 4–7 November, Las Vegas, USA) where Stephen Black (London, UK) and Mitchell Silver (Columbus, USA) discuss the CLEAR-DVT study.  Silver touches on some of the “historic studies” of venous intervention such as ATTRACT and CaVenT and compares them to CLEAR-DVT, which he...
Bentley has announced receipt of the CE mark for its BeYond venous self-expanding stent system. The company will initially launch the stent to an exclusive circle of leading venous experts to gain first-hand experience with this novel device. The first-in-man...
PolarityTE have announced positive results from a protocol-specified interim analysis of the first 50 patients enrolled in a multicentre randomised controlled trial evaluating treatment of diabetic foot ulcers with SkinTE plus standard of care (SOC) versus SOC alone. SkinTE is...
The International Society on Thrombosis and Haemostasis (ISTH), on behalf of the international thrombosis community, have called on the World Health Organisation (WHO) to share learning and support a systematic approach for managing venous thromboembolism (VTE) in patients with...
In a study evaluating rivaroxaban (Xarelto; Bayer) versus warfarin for the treatment and prevention of recurrent venous thromboembolism (VTE) in patients with obesity, results favoured rivaroxaban at three, six, and 12 months. First author Olivia S Costa (University of...
Daiichi Sankyo Europe GmbH has announced results from five analyses of 12-month data from ETNA-VTE (Edoxaban treatment in routine clinical practice in patients with venous thromboembolism), a non-interventional, post-authorisation safety study (PASS) evaluating edoxaban (known by the brand name...
The International Society on Thrombosis and Haemostasis (ISTH) and the American Heart Association (AHA) have released a joint scientific statement identifying the top five priorities for research on venous thromboembolism (VTE); the statement has been published in the ISTH journal Research...
Thrombolex has announced that it was awarded a US$3 million Small Business Innovation Research (SBIR) grant from the National Heart, Lung and Blood Institute (NHLBI) section of the National Institutes of Health (NIH) to fund their pivotal RESCUE trial...
A recent study on iliac vein stenting showed lower long-term patency rates for women when compared to their male counterparts. The data were presented during the Vascular and Endovascular Surgical Society (VESS) session of SVS ONLINE (20 June–2 July)....
Manj Gohel (Cambridge, UK) is joined by a host of venous experts including Beverley Hunt (London, UK), Stephen Black (London, UK) and Ian Franklin (London, UK) to look at the long-term impact of the COVID-19 crisis on the treatment...
A poll of an enthused audience of venous specialists during the CX 2020 LIVE Deep Venous Disease Consensus session found that 91% of them were in favour of using venous stents. Armando Mansilha (Porto, Portugal) chaired the session. Moderator Manj Gohel (Cambridge, UK) subsequently...
   Kathleen Gibson (Bellevue, USA) put the five-year data from the VeClose study, which looked at the treatment of patients with venous reflux in the great saphenous vein (GSV) with either the VenaSeal closure system (Medtronic) or radiofrequency ablation (RFA) therapy,...
Six venous specialists, Manj Gohel (Cambridge, UK), Ian Franklin (London, UK) Alun Davies (London, UK), Sriram Narayanan (Singapore), Raghu Kolluri (Columbus, USA) and Stephen Black (London, UK) discuss the role of telehealth during the COVID-19 crisis and...
Medtronic has announced the first-ever results from the ABRE clinical study assessing the safety and effectiveness of the investigational Abre venous self-expanding stent system in subjects with iliofemoral venous outflow obstruction. The study met the primary safety and effectiveness...
In this issue: Compression stockings might not be needed to prevent blood clots after surgery (p. 1) CX 2020 LIVE brings superficial venous thrombosis to the forefront (p. 1) Paul Gagne considers the future of intravascular ultrasound (IVSU) for...
For the first venous session of CX 2020 LIVE, 759 attendees from 79 different countries tuned in. Each audience member could submit their name, country, and a question or point to the speaker in real-time, enabling interaction, discussion, and...
Transit Scientific has received US Food and Drug Administration (FDA) clearance for the XO Score percutaneous transluminal angioplasty (PTA) scoring sheath platform for use in iliac, ilio-femoral, popliteal, infra-popliteal, and renal arterial plus synthetic and/or native arteriovenous haemodialysis fistula. Angioplasty...
BD has announced the launch of the Halo One thin-walled guiding sheath, designed to perform as both a guiding sheath and an introducer sheath, for use in peripheral arterial and venous procedures requiring percutaneous introduction of intravascular devices. According to...
VisionQuest Biomedical and the University of New Mexico School of Medicine have been awarded a three-year US$3 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH),...
New research published in the New England Journal of Medicine shows that the respiratory virus SARS-CoV-2, which causes COVID-19, causes severe damage to blood vessels, leading to widespread thrombosis, a press release by the Angiogenesis Foundation reports. The study was...
A recent systematic review and meta-analysis showed that, in patients with iliofemoral deep vein thrombosis (DVT), percutaneous mechanical thrombectomy was associated with a higher cumulative six-month primary patency and a lower incidence of major bleeding compared to thrombolysis alone....
Manj Gohel (Cambridge, UK), who is also a member of the CX Venous Executive Board, welcomes you to CX 2020 LIVE, which will include some of the major highlights from the deep and superficial venous programmes. A number of recently...
Venous thromboembolism (VTE) is the leading cause of preventable hospital death in the USA and worldwide. A new policy statement by the American Heart Association provides a focused review of VTE, risk scoring systems, preventive measures for the hospital...
LimFlow SA today announced publication of positive two-year data from the ALPS registry of the LimFlow percutaneous deep vein arterialisation (pDVA) system. Results were published online yesterday in the Journal of Endovascular Therapy and will also appear in the...
Sky Medical Technology highlights a publication on 5 May 2020 in the Journal of Thrombosis and Haemostasis showing the incidence of venous thromboembolism (VTE) in 198 hospitalised COVID-19 patients. The overall rate was 42% at 21 days including patients in...
This video is only available in selected geographies Stephen Black (London, UK) talks to VEITHtv about how the dedicated venous open-cell nitinol Abre stent (Medtronic) compares with other venous nitinol stents available, noting that it is very easy to use,...
Writing for Venous News, Paul Gagne considers the future of intravascular ultrasound (IVUS) based therapies for venous leg ulcers (VLUs). He concludes that while studies of IVUS guided stenting to date "have moved the ball far down the field,"...
The Charing Cross (CX) Symposium, with its world-class faculty and unique focus on live audience participation, has announced the launch of a not-to-be missed and timely vascular and endovascular education virtual event: CX 2020 LIVE. Mark your calendars for this...
Compression stockings might be unnecessary to prevent blood clots in most patients undergoing non-emergency (elective) surgery, finds a clinical trial published by The BMJ today. The results of the Graduated compression stockings as adjuvant to pharmaco-thromboprophylaxis in elective surgical patients...
Control Medical Technology has announced that the US Food and Drug Administration (FDA) has cleared its Aspire MAX 7 – 11F mechanical thrombectomy platform to remove blood clots from peripheral vessels. "This FDA clearance quadruples our product offering and...
Manj Gohel (Cambridge, UK), one of the editors-in-chief of Venous News, introduces a special COVID-19 video with leading thrombosis and haemostasis experts, including Beverley Hunt (London, UK), Ian Franklin (London, UK), Francis Matthey (London, UK) and Sriram Narayanan (Singapore),...
The venous space continues to evolve in the United States, and many physicians are learning how to navigate through the challenges of the venous anatomy from their international peers. As a well-respected expert, the Galway-based interventional radiologist Dr. Gerard...
Venous News talks with Gerard O'Sullivan, FSIR, FEBIR, University College Hospital, Galway, Ireland. This article is supported by BD Interventional. Disclosures: Dr. Gerard O'Sullivan reports he is a consultant/speaker for BD Interventional, Aspirex, Boston Scientific Corporation, Cook Medical, Marvao Medical,...
Prism Schneider (Cumming School of Medicine, University of Calgary, Calgary, Canada) and others write in a commentary in the Canadian Medical Association Journal—because of an increase in domestic violence during the pandemic—healthcare providers should be aware of the signs...
There is an “urgent need” to improve specific venous thromboembolism (VTE) diagnostic strategies and investigate the efficacy and safety of thromboprophylaxis in ambulatory COVID-19 patients. This is the conclusion of a recent study into venous and arterial thromboembolic complications...
A 2020 update on the Clinical-Etiology-Anatomy-Pathophysiology (CEAP) classification system and reporting standards, authored by Fedor Lurie (Jobst Vascular Institute, Toledo, USA; University of Michigan, Ann Arbor, USA) and colleagues, has been published in the Journal Vascular Surgery: Venous and...
On 18 March, the Centers for Medicare & Medicaid Services (CMS) recommended “limiting non-essential care and expanding surge capacity into ambulatory surgical centres and other areas” to conserve resources and staff for managing COVID-19 patients. However, in a statement...
The COVID-19 subcommittee of the American Venous Forum (AVF) has issued a white paper on considerations in prophylaxis and treatment of venous thromboembolism (VTE) in COVID-19 patients. Jeffrey Mendola, director of Mission Advancement at the AVF, emphasises the importance...
Joseph A Caprini considers venous thromboemolism (VTE), patient risk assessment, and therapeutic challenges in the wake of the COVID-19 pandemic, concluding that "accurate thrombosis risk assessment for all coronavirus patients is advised". Emergence of the coronavirus worldwide represents a pandemic...
In a brief report in Annals of Internal Medicine, Seongman Bae (Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea) and colleagues report that neither surgical nor cotton masks appear to be an effective approach for preventing the dissemination of SARS-CoV-2 from...
Manj Gohel, Stephen Black and Alun Davies consider the impact of the COVID-19 pandemic on patients with venous disease. They conclude: "Once the acute crisis has passed, we must work hard as a community to avoid the population of...
Royal Philips has announced that the US government and Philips agreed to team up to increase the production of hospital ventilators in its manufacturing sites in the USA. Philips plans to double the production by May 2020 and achieve...
The European Commission (EC) has adopted a proposal to postpone by one year the date of application of the new Medical Devices Regulation (MDR), which was due to come into force on 26 May this year. The postponement, a press...
In a new statement published on 2 April 2020, all 45 societies represented by the US Council of Medical Specialty Societies (CMSS)—over 800,000 physicians—emphatically declare their belief that all frontline healthcare professionals must have access to personal protective equipment...
The American College of Surgeons (ACS) today leapt to the defense of healthcare workers who are heading to work in the face of increasing concerns over personal protective equipment (PPE) shortages as the COVID-19 pandemic cuts trails across the...
As a podium talk at the annual meeting of the American Venous Forum (VENOUS 2020; 3–6 March, Amelia Island, USA), it represented a bit of an outlier. It was, the presenter admitted, the only non-scientific talk on the programme....
Mechanochemical ablation (MOCA) is a superior option to endovenous laser ablation (EVLA) for the treatment of primary varicose veins, according to the findings of a randomised controlled trial which compared the two modalities. Published in the Journal of Vascular...
It has been found that oral apixaban is noninferior to subcutaneous dalteparin for the treatment of cancer-related venous thromboembolism (VTE), as revealed by Giancarlo Agnelli (University of Perugia, Perugia, Italy) at the American College of Cardiology/World Congress of Cardiology’s...
Results of PRONOMOS, a randomised, controlled, noninferiority trial, have shown rivaroxaban to be more effective than enoxaparin in the prevention of major venous thromboembolic events, during a period of immobilisation after non-major orthopaedic surgery of the lower limbs. The...
During a Q&A section of a European Commission (EC) college meeting on 25 March, EC spokesperson Stefan de Keersmaecker stated that the commission were looking to delay the “entry into force” of the new European medical device regulations (MDR) because of...
A viewpoint in the Journal of the American Medical Association (JAMA) has offered potential solutions to modifying ongoing randomised clinical trials during the COVID-19 pandemic. It aims to “minimise disruption and preserve integrity”, while still ensuring participant health and safety. Authors Mary...
Use of autologous skin cell suspension (ASCS) in addition to compression has been shown to accelerate healing in large venous leg ulcers (VLUs), according to the results of a multicentre randomised trial conducted in the UK. Writing in the...
The American College of Surgeons (ACS) has announced the release of new clinical guidance for surgeons to curtail recommendations for elective surgical procedures, with the aim of preserving necessary resources for the care of critically ill patients during the...
The 2020 Charing Cross (CX) Symposium that was due to take place next month in London, UK, has been cancelled due to COVID-19.  In full, the statement from the CX Symposium team, reads: "The CX Symposium team has made the difficult...
The US Food and Drug Administration’s (FDA) Center for Devices and Radiological Health (CDRH) has written to the medical device industry to outline its response to the COVID-19 public health emergency in its day-to-day operations with industry. The letter from...
Incorporating evidence collected since 2004, the latest revision of the CEAP (Clinical-Etiology-Anatomy-Pathophysiology) classification system has underlined a number of key updates relating to descriptions of chronic venous disease patients. “There has been a lot of information that has come...
“We found deficiencies in current indications for intervention, which may explain some of the overutilisation we have been encountering,” explained Elna Masuda (Straub Medical Center, Hawaii Pacific Health, Honolulu, USA), during an overview of the new 2020 appropriate use...
The Lindsay Leg Club Foundation has launched a new fundraising campaign in partnership with the Aviva Community Fund, in a bid to raise money for a new Leg Club. There are currently 44 Leg Clubs operating throughout the UK,...
According to a network meta-analysis, the VenaSeal system (Medtronic) is “a promising therapeutic option for anatomic success at six months”. This study, published in the Journal of Vascular Surgery: Venous and Lymphatic Disorders, also highlighted the lower number of...
Results of a 12-month study conducted by a group of Commonwealth physicians have demonstrated that endovenous valve formation in the deep venous system is feasible. Presented in the International Session at the annual meeting of the American Venous Forum...
Symptoms of restless leg syndrome are 34.5% more prevalent in patients with superficial venous insufficiency, according to a retrospective study presented by Aaron Dezube (St Elizabeth Medical Center, Brighton, USA). Although restless leg syndrome was identified in those without...
Thrombolex has announced that results of its First-In-Human (FIH) trial confirm the early safety and feasibility of using the Bashir Endovascular Catheter for pharmacomechanical catheter-directed thrombolysis (CDT), in patients with acute pulmonary embolism (PE). The data, presented at the...
“Venous leg ulcers (VLUs) secondary to deep venous stenosis represents a distinct class of patients who require a unique treatment paradigm,” stated Abhisekh Mohapatra (University of Pittsburgh Medical Center, Pittsburgh, USA), presenting results of a multicentre retrospective study of...
A retrospective review of patients presenting with bilateral obstructive iliofemoral venous lesions has shown that contralateral limb symptoms improve following stenting of the worse ipsilateral limb. In addition to this, the study found that only a small proportion of...
In a case-control study of patients with perceived contraindications to anticoagulation, who either received or did not receive inferior vena cava (IVC) filters, no difference was found in the incidence of symptomatic pulmonary embolism (PE) at 90 days. Presented...
Access Vascular has announced that it has received clearance from the US Food and Drug Administration (FDA) for the second generation of its HydroPICC peripherally inserted central catheter (PICC), which has demonstrated a thrombus accumulation rate 30 times less...
MolecuLight has announced the release of a "significant upgrade" to its I :X digital wound measurement feature that enables clinicians to more accurately and quickly capture digital wound area measurement. According to a statement, clinicians can now reliably detect more...
ATTRACT compared outcomes following pharmacomechanical thrombolysis (PMT) versus standard medical therapy (SMT), and while no benefit with PMT was demonstrated for femoropopliteal deep vein thrombosis (DVT), subgroup analysis of iliofemoral DVT demonstrated a reduction in moderate-to-severe post thrombotic syndrome...
Use of the ClotTreiver system (Inari Medical) for the treatment of lower extremity deep vein thrombosis (DVT) has demonstrated safety and efficacy, especially in “removing large volumes of lower extremity acute thrombus in a single session”. A retrospective review...
Investigators in The Netherlands, France and Belgium have developed a risk assessment model for venous thromboembolism (VTE). Published by The Lancet in EClinicalMedicine, the TRiP(cast) score (thrombosis risk prediction following cast immobilisation) is described as “a helpful tool in...
A retrospective analysis of patients diagnosed with lower extremity lymphoedema, and treated in a cancer-affiliated physical therapy department, has found that chronic venous insufficiency (or phlebolymphoedema) is the “predominant cause of lower extremity lymphoedema”. Published online in the Journal...
Following the publication of “Another nail in the coffin of vena cava filters” in the British Journal of Surgery, which considered potential problems with the use of inferior vena cava (IVC) filters, authors Andrew Doyle and Narayan Karunanithy (Guy’s...
Bluegrass Vascular Technologies (Bluegrass Vascular) announced today that the US Food and Drug Administration (FDA) has granted a de novo classification order for its Surfacer Inside-Out access catheter system. The Surfacer system is intended to obtain central venous access...
XableCath has announced that its XableCath Crossing catheters have received CE mark for peripheral use. Its crossing devices will be available for sale in Europe in two versions, a blunt tip and an abrasion tip, in a variety of...
Venous News filmed a panel discussion with Alun Davies (London, UK), Manj Gohel (Cambridge, UK) and Daniel Carradice (Hull, UK); who discussed treatment of venous ulceration and the randomised EVRA trial which, Carradice says, showed that early endovenous ablation of superficial venous...
“We need to check for signs of recurrence and functional impairment, and follow these patients much more closely,” urged Kenneth Rosenfield (Massachusetts General Hospital, Boston, USA), speaking on the long-term outcomes for pulmonary embolism (PE) patients at the International...
 Michael Lichtenberg (Arnsberg, Germany) talks to BLearning Venous at LINC 2020 (Leipzig Interventional Course; 28–31 January 2020, Leipzig, Germany) about the rationale behind his team’s study which looked at Intravascular ultrasound (IVUS) compared with fluoroscopic-guided recanalisation in patients with...
According to the findings of a European multicentre retrospective analysis, the use of drug-coated balloons (DCBs) for the treatment of symptomatic central venous stenosis in dialysis patients has been demonstrated as safe. Presented at the Leipzig Interventional Course 2020...
“When we are talking about varicose veins, we are talking about patients, all of whom have different patterns of varicose veins,” stated Armando Mansilha (University of Porto, Porto, Portugal), responding to the argument of Thomas Proebstle (University of Mainz,...
Clinical outcomes with the Vici venous stent system (Boston Scientific) have been described as “very good”, according to a presentation of 24- and 36-month follow-up data at the Leipzig Interventional Course 2020 (LINC; 28–31 January, Leipzig, Germany). During his...
Biolitec has announced the addition of another laser fibre to its ELVeS Radial 2ring laser fibre range. The ELVeS Radial 2ring Pro enables the minimally invasive endovenous laser treatment of severely tortuous veins. According to a press release, the ELVeS...
 Raghu Kolluri (Columbus, USA) and John Kaufman (Portland, USA) talk to BLearning Venous about the highlights from The VEINS (Venous Endovascular INterventional Strategies) session at VIVA 2019 (Vascular InterVentional Advances; 4–7 November, Las Vegas, USA), as well as the...
Initial results of an ongoing first-in-man study in Colombia, that saw the implantation of a prosthetic venous valve in 15 patients, have demonstrated an improvement in clinical outcomes and quality of life. The promising findings were presented to delegates...
Sky Medical Technology has announced that the geko device was presented as part of the didactic program, and at a corporate-sponsored symposium, at the Orthopaedic Summit 2019: Evolving Techniques (OSET 2019) annual meeting (December 11–14, Las Vegas, USA). Jason Snibbe, a...
A retrospective analysis of patients treated with ultrasound-guided foam sclerotherapy (UGFS), published in the January 2020 issue of Phlebology, has found that the frequency of non-target vein occlusions following this procedure—revealed by serial duplex ultrasound (DUS)—could be as high...
Argon Medical Devices has announced the commercial launch of its Single-loop and Triple-loop retrieval kits for sale in the USA. The Single-loop and Triple-loop Retrieval Kits are intended for percutaneous removal of retrievable inferior vena cava (IVC) filters that...
Raghu Kolluri vascular medicine profile

Raghu Kolluri

Following his recent appointment as president of the Society for Vascular Medicine (SVM), Raghu Kolluri (Columbus, USA) speaks to Venous News about how the venous field is being affected by the results of recent trials, his involvement with The...
The “Standard versus ultrasound-assisted catheter thrombolysis for submassive pulmonary embolism” (SUNSET sPE) trial, a randomised, single-blinded clinical trial comparing ultrasound-assisted thrombolysis (USAT) to standard catheter-directed thrombolysis (SCDT), has completed enrolment, as announced on Friday 17 January by principal investigators...
In this issue of Venous News: CAVA trial: CDT does not change post-thrombotic risk for iliofemoral DVT patients Restless legs study establishes association with reflux of lateral subdermic plexus Manj Gohel and Stephen Black: Where does the CAVA trial leave us? ...
In this issue of Venous News: CAVA trial: CDT does not change post-thrombotic risk for iliofemoral DVT patients Restless legs study establishes association with reflux of lateral subdermic plexus Manj Gohel and Stephen Black: Where does the CAVA trial leave us? ...
Penumbra has announced US Food and Drug Administration (FDA) 510(k) clearance for expanded indication of the Indigo Aspiration System. As part of the system, Indigo Aspiration Catheters and Separators are indicated for the removal of fresh, soft emboli and...
With the level of spending on wound care in the billions of pounds, both the financial and health-related impact of venous leg ulcers cannot be understated. Dan Carradice (Hull York Medical School, Hull, UK) speaks to Venous News about...
Results from the Dutch CAVA trial were published recently in The Lancet Haematology and, at first glance, this is another trial that failed to demonstrate any meaningful benefit for early thrombus removal in patients with acute iliofemoral deep vein...
Serena Auñón-Chancellor, clinical associate professor of medicine at Louisiana State University Health, New Orleans School of Medicine’s branch campus, in Baton Rouge, USA, is the lead author of a paper which describes a previously unrecognised risk of spaceflight discovered...
An analysis of data from the ATTRACT trial, published in the Journal of Vascular Surgery: Venous and Lymphatic Disorders (JVSVL), reveals that quality of life measures improve after pharmacomechanical catheter-directed thrombolysis (PCDT). According to the findings of the analysis,...
Insera Therapeutics’ CLEAR aspiration system has been used for the first time to treat a (human) patient with acute pulmonary embolism (PE). CLEAR, “cyclical luminal, evaluation, aspiration, and retrieval”, is a digital vacuum aspiration system that allows operators to...
The US Food and Drug Administration (FDA) has announced the approval of two applications for the first generics of Eliquis (apixaban) tablets, to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Apixaban is also...
Bluegrass Vascular Technologies, a private medical technology company focused on innovating devices and methods for vascular access procedures, has announced the publication of positive results associated with a clinical study involving the use of the Surfacer Inside-Out Access Catheter...
“The goal needs to remain on improving healing, but also reduced recurrence in the long term,” said Stephen Black (Guy’s and St Thomas’ Hospital, London, UK), during his presentation of results from the Leg Ulcer Pathway Audit (LUPA) study...
Narayan Karunanithy outlines the benefits of intravascular ultrasound (IVUS) during haemodialysis access intervention. Thoracic central veins include intra-thoracic segments of the internal jugular, subclavian, brachiocephalic veins and superior vena cava. These veins are located central to the superior thoracic aperture...
  Thrombolex has announced that the company has received US Food and Drug Administration (FDA) clearance for the Bashir Endovascular Catheter - Short Basket (BEC S-B). The indication for use of the BEC S-B is for the controlled and selective...
While the treatment of spider, reticular and varicose veins using sclerotherapy has been a standard practice for many years, tumescent enhanced sclerotherapy has been developed as an office-based technique that takes traditional sclerotherapy a step further by applying a...
Results of a randomised controlled trial conducted at Imperial College, London, UK, have shown that the application of compression stockings is associated with a significant reduction in pain during the first few days following intervention. In addition, it was...
Based on the results of a retrospective, single-centre cohort study conducted at The RANE Center, St Dominic’s Memorial Hospital (Jackson, Mississippi, USA), the importance of intravascular ultrasound (IVUS) for identifying the location and severity of stenotic lesions in the...
Insera Therapeutics announced recently that the first patient with acute pulmonary embolism has been treated with its flagship cyclical aspiration system, CLEAR. Earlier last month, the first two stroke patients were treated using the same platform. The company received...
Additional ultrasound-accelerated catheter-directed thrombolysis (CDT) does not change the risk of post-thrombotic syndrome in patients with acute iliofemoral deep vein thrombosis (DVT) at one-year follow up, compared with standard therapy alone, according to findings of the CAVA trial published...
There are “significant limitations” to the use of duplex ultrasound for the initial evaluation of patients with suspected subclavian vein (SCV) thrombosis, according to the findings of a retrospective, single-centre review published in the Journal of Vascular Surgery: Venous...
Writing to members of the American Venous Forum (AVF), president Brajesh K Lal (Baltimore, USA), has revealed that the AVF has established a partnership with the C-TRACT study, a randomised controlled trial funded by the National Institutes of Health....
Long-term evaluation of superficial venous reflux below the knee, in patients who received invasive treatment for varicose veins, has found that both radiofrequency ablation (RFA) and open surgery achieve "acceptable and comparable results" in the elimination of reflux in...
In the treatment of reticular veins of the lower extremities, using polidocanol foam, it has been found that both a 1:2 ratio and 1:4 ratio of polidocanol to air demonstrate similar levels of efficacy and safety. According to presenter...
Findings of a recent study on whether a pathologic perforator can predict the presence of an ipsilateral central venous stenosis, as presented at the annual meeting of the American Vein and Lymphatic Society (AVLS; 7–10 November 2019, Arizona, USA),...
Implementation of an evidence-based pathway for leg ulcer care in community nursing has resulted in a significant reduction in healing times, according to research conducted by the Manchester University NHS Foundation Trust, Manchester, UK. Although quality of life scores...
John-Kaufman-profile

John Kaufman

As course director of The VEINS at VIVA 2019 (2–4 November, Las Vegas, USA), John Kaufman tells Venous News how the field of interventional radiology (IR) has transformed over the years and highlights key areas of innovation to look...
Miles D White will be stepping down, after 21 years, as CEO of Abbott on 31 March 2020. According to a press release, White’s tenure is the second longest for a non-founder in today’s S&P 100; he will remain...
Reflux of the lateral subdermic plexus—varicose veins which appear on the outside of the thigh and calf—could be closely related to the symptoms of restless leg syndrome and night-time cramping, according to a review conducted on prospective symptom tracking...
Clinically relevant outcomes are needed to measure catheter-directed therapy (CDT) against anticoagulation alone to treat submassive pulmonary embolism (PE) patients. Further, CDT’s ability to affect short-term and long-term outcomes such as cardiopulmonary health after PE needs “better characterisation”, Akhilesh...
David J. Dexter, (Sentara Healthcare, Norfolk, VA, USA), principal investigator of the CLOUT registry using the ClotTriever Mechanical Thrombectomy System (Inari Medical) for treatment of acute and chronic lower extremity DVT, presented the initial results for the first 50...
 Suresh Vedantham (St Louis, USA) talks to BLearning Venous after winning the prestigious VEINS award at VIVA 2019 (Vascular InterVentional Advances; 4–7 November, Las Vegas, USA) about his current take on the open vein hypothesis and more. Vedantham reflects on...
In this issue of Venous News: Future trials on DVT management "have to focus on technical success" Foam "has not been established as superior" to liquid sclerotherapy Manj Gohel: A look at new preliminary guidelines for SVT Anelise Rodrigues: Augmented reality...
In this issue of Venous News: Future trials on DVT management "have to focus on technical success" Foam "has not been established as superior" to liquid sclerotherapy Manj Gohel: A look at new preliminary guidelines for SVT Anelise Rodrigues: Augmented reality...
Inari Medical has announced the presentation of early outcomes from the ClotTriever Outcomes Registry (CLOUT) using the ClotTriever Mechanical Thrombectomy System for treatment of acute and chronic lower extremity deep vein thrombosis (DVT). Initial results for the first 50...
It has been found by the EXTRACT-PE trial, a multicentre investigation conducted under an investigational device exemption (IDE) from the US Food and Drug Administration (FDA), that aspiration thrombectomy for acute pulmonary embolism (PE) with the Indigo Aspiration System...
A Philadelphia jury has awarded more than US$33 million to a woman who was injured as a result of a defectively designed inferior vena cava (IVC) filter. The trial was overseen by Philadelphia Judge Michael Erdos. The litigation focused on...
Analysing the results of a retrospective, single-centre cohort study conducted at Guys and St Thomas’ Hospital, London, UK, Anna Pouncey (Guys and St Thomas’ Hospital, London, UK) emphasised that over 50% of cases included in the investigation could have...
Speaking at the annual meeting of the Cardiovascular and Interventional Radiological Society of Europe (CIRSE 2019; 7–11 September, Barcelona, Spain), Stephen Black (Guys and St Thomas’ Hospital, London, UK) emphasised that “ATTRACT and CAVA are not the end of...
It has been found that the application of dehydrated human amnion and chorion allografts (dHACA) results in a better venous leg ulcer (VLU) healing rate than the use of standard multilayer compression therapy, following a randomised controlled study comparing...
Current classification tools for the diagnosis of chronic venous disease, including acute deep vein thrombosis (DVT) and post-thrombotic syndrome (PTS), include “redundant” elements that are unimportant to patients, according to an address delivered by Mark Meissner (Seattle, USA) at...
Venarum Medical has announced that it has received a mentorship grant in further support of its awarded Phase II SBIR Grant “EVVS: EndoVenous Valve System”, which is currently underway. Under its Phase II work, Venarum proposes to verify the preclinical...
A report titled ‘Venous Leg Ulcers: A Silent Crisis’ has been published by the All-Party Parliamentary Group on Vascular and Venous Disease (VVAPPG) at an event held at the Palace of Westminster, highlighting the opportunities available to help thousands...
At the European Society of Vascular Surgery annual meeting (ESVS 2019; ­24­­-27 September, Hamburg, Germany), preliminary venous thrombosis guidelines were presented for the first time. Chaired by Stavros Kakkos (Patras, Greece) and Manj Gohel (Cambridge University Hospitals, Cambridge, UK),...
Indocyanine green dye (ICG) fluorescence lymphography represents a suitable method of providing information on the effectiveness of intermittent pneumatic compression (IPC) during the treatment of leg oedema (an excess of fluid around the limb), according to a study conducted...
STARmed has announced that it has obtained CE Mark approval for VENISTAR, an "innovatively designed" electrode that uses radiofrequency energy to treat patients with damaged veins. According to a statement, this minimally invasive electrode provides physicians with the ability...
PolarityTE, a company specialised in regenerative tissue products and biomaterials, has announced findings from an open-label, single-arm pilot study, which examined the impact of SkinTE in closing venous stasis leg ulcers (VLUs) following the failure of conventional treatments. The clinical outcomes...
A pilot evaluation of a new multilayer wound dressing has confirmed its efficacy for transporting exudate containing toxic matrix metalloproteases (MMPs) away from chronic venous leg ulcers (VLUs). Conducted by Oscar M Alvarez (University Hospital; Rutgers New Jersey Medical...
UK-based Sky Medical Technology has received US Food and Drug Administration (FDA) 510(k) clearance for its "geko" device for stimulation of the calf muscles to prevent venous thrombosis in non-surgical patients at risk for venous thromboembolism (VTE). This adds...
Speaking at the International Union of Phlebology chapter meeting (UIP 2019; 25–27 August, Krakow, Poland), Neil Khilnani (New York, USA) underlined that the current literature on sclerotherapy, in addition to guidelines from the European Consensus and American Society for...
Kurosh Parsi profile

Kurosh Parsi

Kurosh Parsi, incoming president of the International Union of Phlebology, or Union Internationale de Phlebologie (UIP), is an Australian dermatologist, phlebologist and vascular anomalies specialist who pioneered catheter-guided and tumescent-assisted sclerotherapy. With his broad range of expertise and varied...
Clinical data presented at the 2019 European Cardio-Thoracic Surgery (EACTS) annual meeting (3-5 October, Lisbon, Portugal), from two prospective trials of the VEST external stent for vein grafts during coronary artery bypass surgery (CABG), showed low major adverse cardiac...
At the 2019 Transcatheter Cardiovascular Therapeutics (TCT) meeting (25–29 September, San Francisco, USA), InterVene won the TCT-Shark Tank Innovation Competition for its novel endovenous system (BlueLeaf) for forming valves in patients with deep vein reflux and/or chronic venous insufficiency. The award, which...
In this issue of Venous News: SUPER trial demonstrates benefits of intermittent pneumatic compression "Fascinating vision" of non-invasive varicose vein treatment Oliver Lyons: Pharmacotherapy for lymphoedema Efthymios Avgerinos: SUNSET sPE interim outcomes Profile: Kurosh Parsi
In this issue of Venous News: SUPER trial demonstrates benefits of intermittent pneumatic compression "Fascinating vision" of non-invasive varicose vein treatment Oliver Lyons: Pharmacotherapy for lymphoedema Efthymios Avgerinos: SUNSET sPE interim outcomes Profile: Kurosh Parsi
Like many other industries, the shape of healthcare and medicine is being transformed by the emergence of new technologies. Phlebology, as Anelise Rodrigues (Culabá, Brazil) explains, is no different. While there are still concerns with the potential limitations and...
Laser crossectomy of the GSV has been established as a more effective method of preventing secondary anterior accessory great saphenous vein (AAGSV) reflux than treatment modalities which leave stumps. As part of a randomised controlled study comparing the technique...
Bluegrass Vascular Technologies (Bluegrass Vascular) has announced the publication of positive results associated with the clinical use of the Surfacer Inside-Out access catheter system in the peer-reviewed Journal of Vascular Access (JVA). Results of an independent, single-centre study demonstrated successful use...
The Janssen Pharmaceutical Companies of Johnson & Johnson has announced the publication of new real-world evidence which confirms that XARELTO (rivaroxaban) reduces the risk of recurrent venous thromboembolism (VTE) in patients who are morbidly obese, with effectiveness and safety...
 Sanjay Misra (Rochester, USA) talks to Interventional News about his research into whether stem cell therapy can help AVFs (arteriovenous fistulas) mature and also prevent venous stenosis. The pilot study with a small group of haemodialysis AVF patients led to “promising...
While compression therapy is of the treatment options for patients suffering with venous insufficiency and chronic wounds, this could also present benefits for healthy subjects. Following his presentation at the International Union of Phlebology chapter meeting (UIP 2019; 25–27...
There is no significant difference in pain and recanalisation for patients undergoing endovenous laser ablation (EVLA) at different power settings, according to the results of a new randomised controlled clinical trial. This investigation was conducted following a previous morphological...
Evidence from a recent study conducted by Imperial College London, UK has further demonstrated that the Villalta scoring system is not disease-specific and correlates with other tools for measuring venous outcomes. The results of the study have implications for...
PIUR Imaging has launched a portable version of its tomographic ultrasound system to the European market. The new CE-marked PIUR tUS Infinity is a small, wireless version of its tomographic ultrasound solution that turns any standard ultrasound into a...
Omar Ishrak, Medtronic’s chairman and CEO is to retire on 26 April 2020, following the end of the company’s current fiscal year. Also, the Medtronic Board of Directors has announced key leadership appointments as part of its multi-year, leadership...
 Michael Dake (Tucson, Arizona) presented the two-year data from the VERNACULAR trial at CIRSE 2019 on 8 September in Barcelona, Spain. Dake said: “The 24-month results from the VERNACULAR trial using the BD Venovo stent show absolutely sustained benefit in...
Boehringer Ingelheim has announced the publication of primary analysis from RE-SPECT CVT, the first exploratory, prospective, randomised controlled study of a NOAC in patients with blood clots in the veins or venous sinuses of the brain. The trial investigated...
An updated guideline on the prophylaxis and treatment of venous thromboembolism (VTE) in patients with cancer has been unveiled by the American Society of Clinical Oncology (ASCO) in its Journal of Clinical Oncology. An expert panel convened by ASCO...
A study into the efficacy of early reflux elimination for venous leg ulcer (VLU) patients has revealed that the combination of ultrasound-guided foam sclerotherapy (UGFS) only, and a hybrid method of endovenous laser treatment (EVLT) with UGFS, could present...
A private equity firm, Palatine (Manchester, UK), has announced that it has made a “significant investment” into a UK centre—Veincentre—that provides endovenous laser ablation (EVLA) for the management of varicose veins.  The investment, according to Palatine, is the fourth...
Results from two open prospective trials have revealed that TLC-NOSF sucrose octasulphate dressing, with poly-absorbent fibres, represents an effective and safe treatment for the local management of leg ulcers. In addition, cost-effectiveness studies examining the economic impact of the...
While developing specific treatment for primary lymphoedema presents an “enormous” scientific challenge, secondary lymphoedema may prove an easier target, Oliver Lyons writes for Venous News. In this article, Lyons outlines what is currently known, and what to expect in...
Certain reflux patterns in patients with chronic venous disease can be associated with increased clinical severity and a lower quality of life, according to the results of a recent study conducted at Imperial College London, UK. As part of...
Thrombolex has announced the enrolment of the first patient in their Early Feasibility and Safety Study, investigating the Bashir Endovascular Catheter for the treatment of submassive pulmonary embolism (PE). The device was designed to quickly and safely dissolve thrombus...
A member of the UK parliament has emphasised the need for a national wound care strategy during a recent debate in the House of Commons, highlighting that “diagnosis is difficult, but rapid diagnosis is absolutely essential”. Ann Clywd, MP...
 Karen Bauer (Toledo, USA) discusses the wound care limb salvage track at C3 which offered the “opportunity for clinicians from multiple disciplines to get together and talk about some really cutting-edge” topics. Bauer, a wound specialist, says that at the...
In her presentation at the Royal Society of Medicine Venous Forum (RSMVF; 17–19 June, London, UK), consultant vascular surgeon Emma Wilton (Oxford University Hospitals, Oxford, UK) outlined the important process for identifying which patients with leg ulceration require deep...
Endovenous laser ablation (EVLA) of perforating veins has been further established as an effective method of treating chronic venous ulcers in patients with diabetes mellitus, according to a new study conducted in Azerbaijan. Results of the study, which involved 42...
A recent study has concluded that patients with inherited or acquired thrombophilia should not be excluded from ilio-femoral venous stenting, Adam Gwozdz (St Thomas’ Hospital, London, UK) reported at the European Venous Forum (EVF; 27–29 June, Zurich, Switzerland). “By...
The Janssen Pharmaceutical Companies of Johnson & Johnson announced today new results from the Phase 3 EINSTEIN-Jr study, showing paediatric patients (aged birth to 17 years) treated with rivaroxaban (brand name Xarelto) had a similar low risk of recurrent...
A US-based multicentre study has found that while chronic venous insufficiency is “primarily observed in white women”, there are other notable differences in the incidence and prevalence of disease severity and outcomes when comparing patients’ racial groups, with African...
 Rabih Chaer (Pittsburgh, USA) talks to Venous News at the Society for Vascular Surgery’s Vascular Annual Meeting (SVS VAM; 12–15 June 2019, Washington, DC, USA)about the “need for dedicated venous stents” in the US in anticipation of the recently US FDA approved...
InterVene has announced it has raised US$15 million in a Series B financing round. The company’s BlueLeaf Endovenous Valve Formation System is the first catheter-based solution for deep venous reflux that does not require an implant. The system is designed to correct one...
The new West London Vascular and Interventional Centre at Northwick Park Hospital (Harrow, UK) has officially been declared open. As of the 25th June, 2019, patients who require vascular treatment will be able to benefit from the modern facilities...
Siemens Healthineers and Mentice AB have announced that they are collaborating to fully integrate Mentice’s VIST virtual patient into the Artis icono angiography system from Siemens Healthineers. According to a press release, the VIST virtual patient thus becomes a fully...
Catheter-directed thrombolysis improves outcomes and long-term cost efficiency for treatment of massive and submassive pulmonary embolism (PE), in comparison to systemic heparin administration. This was the conclusion of study investigators led by Patrick Kelly (Sanford Health, Sioux Falls, USA),...
The Standard vs ultrasound-assisted catheter thrombolysis for submassive pulmonary embolism (SUNSET sPE) trial, is an ongoing randomised, head-to-head, single-blinded clinical trial comparing ultrasound-assisted thrombolysis to standard catheter-directed thrombolysis. While comparative data is not yet available, Efthymios "Makis" Avgerinos (University...
In this issue: - "Urgent action" is required to improve referral for venous ulcer patients - VenaSeal maintains safety and efficacy at extended five-year follow-up - Dominik Heim: The 20th European Venous Forum (EVF) - Raghu Kolluri: The role of elevated central venous...
In this issue: - "Urgent action" is required to improve referral for venous ulcer patients - VenaSeal maintains safety and efficacy at extended five-year follow-up - Dominik Heim: The 20th European Venous Forum (EVF) - Raghu Kolluri: The role of elevated central venous...
The TLC-NOSF (UrgoStart, Urgo Medical) advanced wound care dressing was recently recommended by the UK National Institute for Health and Care Excellence (NICE) for healing of venous and diabetic foot ulcers. Speaking at the European Wound Management Association annual...

Fedor Lurie

Fedor Lurie started his medical career in Ekaterinburg, Russia, on the east side of the Ural mountain chain. Now a long-time prominent figure in some of the largest venous and vascular societies in the USA, Lurie speaks to Venous...
Steven Dubenec (Sydney, Australia) and Gerard O’Sullivan (Galway, Ireland) discuss the impact of dedicated venous stents, in particular the Venovo venous stent (BD, formerly Bard) at CX 2019. Dubenec talks about how the Venovo stent – which comes in a...
The last two decades have seen a major revolution in the treatment of varicose veins and venous reflux disease—and we may be on the brink of the next big shift. This is what Mark S Whiteley writes for Venous...
 Michael Edmonds (London, UK), Thomas Serena (Warren, USA), Keith Harding (Cardiff, UK), and Williams Ennis (Oak Lawn, USA) talk at CX Live about the first ever iWounds workshop, the importance of wound management and what they hope to achieve. Edmonds...
A new study has found that intensive care unit patients with swine flu (H1N1) and acute respiratory distress syndrome (ARDS) were 33 times more likely to develop venous thromboembolism (VTE), unless prescribed with an anticoagulant when admitted. The findings were...
Vesper Medical, a developer of medical devices for minimally invasive peripheral vascular procedures, has announced a US$37 million financing with Vensana Capital and Gilde Healthcare as lead investors. They were joined by existing investors New Enterprise Associates (NEA) and...
In this article for Venous News, Dominik Heim spoke to Michel Perrin and Bo Eklöf about the founding of the European Venous Forum (EVF; 27–29 June, Zürich, Switzerland), an international symposium for venous specialists that this year celebrated its...
Defining success in venous ulcer healing, and for all chronic wounds, remains a nebulous concept—with no consensus on what constitutes a successful outcome. Dave Bosanquet (Bristol, UK) outlined the difficulties at the Charing Cross Symposium (CX; 15–18 April, London,...
A new treatment modality is aiming to take the idea of minimally-invasive procedures to the next level for treatment of varicose veins and venous insufficiency. Alfred M Obermayer of the Institute of Functional Phlebosurgery, Karl Landsteiner Society in Vienna,...
Thrombolex has announced that the US Food and Drug Administration (FDA) has cleared the Bashir Endovascular Catheter (BEC) for the controlled and selective infusion of physician-specified fluids, including thrombolytics, into the peripheral vasculature, and the Bashir N-X Endovascular Catheter...
Inari Medical has announced the publication of its 106-patient prospective multicentre FlowTriever Mechanical Pulmonary Embolectomy (FLARE) study for the treatment of intermediate-risk pulmonary embolism (PE). The study was published in JACC: Cardiovascular Interventions. FLARE was conducted under the direction...
Boston Scientific has announced hat the US Food and Drug Administration (FDA) has approved the Vici venous stent system for the treatment of iliofemoral venous obstructive disease. Venous obstructive disease affects nearly 40% of the population in the USA and...
Also known as "Vein Specialists Sitting around Talking and Having Drinks," the VEIN Magazine Podcast with Steve Elias features real discussions on venous disease and treatment. Once a month, this podcast brings together leaders in the venous treatment world...
Prakash Saha (London, UK), speaking during the Venous and Lymphatic Challenges programme at CX (15–18 April, London, UK), outlined the three key steps to optimising treatment of acute deep vein thrombosis: identification, management, and surveillance. He added that the...
Raghu Kolluri gives an overview of elevated central venous pressure—a condition which Kolluri argues is elusive, underdiagnosed and in need of further examination in order to establish its role and relationship to chronic venous insufficiency. It is not uncommon to...
“A lot more bacteria than anticipated” have been discovered on wounds in a patient cohort consisting of 89% venous leg ulcers, and using fluorescence imaging proved superior for detecting infection in wounds. This was the conclusion of Tomas Serena (Warren,...
Despite what current guidelines denote, and in addition to the emergence of data supporting the early intervention of venous ulceration, Alun Davies (London, UK) put forward that the recommendations are consistently being ignored, and highlighted that: “Urgent action is...
The first-ever 60-month data on Medtronic’s VenaSeal closure system were presented on Tuesday, indicating that at five years, treatment with the cyanoacrylate adhesive for closure of diseased vein segments was not inferior to the alternative treatment arm of radiofrequency...
Speaking at the Charing Cross International Symposium (CX; 15–18 April, London, UK), Isaac Nyamekye (Worcester, UK) presented the results of the 3RF study, which compared three radiofrequency ablation systems (Venefit, RFITT, and EVRF). Nyamekye reported that compared with the...
A recent paper published by Hakan Duman (Recep Tayyip Erdoğan University, Rize, Turkey) and colleagues in the Journal of Vascular Surgery: Venous and Lymphatic Disorders has concluded that lower levels of bilirubin were significantly associated with venous thromboembolism (VTE),...
 Michael D Dake (Tucson, USA) presented results from the VERNACULAR trial, which was designed to assess the performance of the Venovo venous stent (BD) for the treatment of iliac and femoral vein occlusions. At one year, the researchers found that the...
 Mahmood Razavi (Orange, USA) reported new data from a subanalysis of the VIRTUS trial, which set out to investigate the safety and efficacy of the Vici stent (Boston Scientific). The subanalysis forms part of the first prospective multicentre corelab...
Kasuo Miyake is a leader in Cryo-Laser and Cryo-Sclerotherapy (CLaCS) treatments for varicose veins. Based in Sāo Paulo, Brazil, Miyake heads the vein clinic founded by his late father, Hiroshi Miyake, a pioneer in the field of CLaCS and...
Healogics, a provider of advanced chronic wound care services in the USA, has announced they have added vein ablation to their in-house service offerings through a new programme called Healogics VeinCare. This programme allows the company to provide patients...
BD has announced that the US Food and Drug Administration (FDA) has granted premarket approval for the Venovo venous stent, the first stent indicated to treat iliofemoral venous occlusive disease. The Venovo venous stent is a flexible nitinol stent specifically...
The CASSINI trial found that treatment with rivaroxaban did not significantly reduce the incidence of thromboembolism or death caused by thromboembolism in high-risk ambulatory patients with cancer during the 180-day study period. However, during the study’s intervention period, there...
The commissioner of the US Food and Drug Administration (FDA), Scott Gottlieb, has unexpectedly resigned after serving just shy of two years in the post. Gottlieb announced his intention to stand down in a letter to Alex Azar II, the...
At the 2018 Vascular Societies’ Annual Scientific Meeting (VSASM; 27–29 November, Glasgow, UK), Bruce Campbell from Exeter Medical in Exeter, UK, who previously chaired National Institute for Health and Care Excellence (NICE) advisory committees for interventional procedures and medical...

Johann Chris Ragg

Johann Chris Ragg speaks to Venous News about the innovations he pioneered and the work that inspired his projects, as well as the challenges and benefits of running a private vascular clinic specialising in endovenous treatments. Ragg recounts his...
In this issue: New ATTRACT data show greater benefits of catheter-based therapy for iliofemoral DVT patients NICE aortic guidelines debate prompts scrutiny of venous guidelines and evidence gaps Thom Rooke: Avoiding sclerotherapy complications Profile: Johann Chris Ragg  

Venous News 9 – January 2019

In this issue: New ATTRACT data show greater benefits of catheter-based therapy for iliofemoral DVT patients NICE aortic guidelines debate prompts scrutiny of venous guidelines and evidence gaps Thom Rooke: Avoiding sclerotherapy complications Profile: Johann Chris Ragg  
The UK's National Institute of Health and Care Excellence (NICE) has published new guidance recommending UrgoStart wound dressings (Urgo Medical) for treatment of diabetic foot ulcers and venous leg ulcers. In a press release, Urgo Medical states that use...
The editors-in-chief of major cardiovascular journals—of both US and European societies—have come together to “sound the alarm” about the dangers of medical misinformation that has been disseminated through the internet, social media, and other platforms. They claim that this...
Philips launches its Azurion with FlexArm to aid patient imaging and positioning during image-guided procedures. During increasingly complex interventions, clinicians need to quickly and easily visualise critical anatomy and identify changes to the patient during the procedure. Azurion with FlexArm...
Medical device company Hancock Jaffe has announced the end-points for its upcoming VenoValve first-in-human study in Bogota, Colombia. Endpoints for the study will include improvements in reflux time, as well as three venous clinical measurement tools: the revised Venous...
Speaking at the Leipzig Interventional Course (LINC; 22–25 January, Leipzig, Germany), Katja Mühlberg of the University of Leipzig, Germany, called for an improvement in the evidence base around the role of compression in healing venous leg ulcers (VLU). Mühlberg...
New 12-month data from the VIRTUS trial demonstrates that patients who were treated with the Vici Venous Stent system (Boston Scientific) for iliac and femoral vein obstructions exhibited a high rate of patent, or open, target lesions. Primary safety and...
The US government shutdown means the country’s Food and Drug Administration (FDA) cannot accept new user fees, which means the agency cannot accept new medical product applications. FDA commissioner Scott Gottlieb took to Twitter to highlight agency employees who are...
The first-in-human case using the new deep vein thrombosis (DVT) device Vetex thrombectomy catheter (Vetex Medical) has recently been completed in a multicentre study. The device has the potential to reduce hospital stays and costs associated with DVT treatment,...
A single-centre experience using large, braided self-expanding stents for iliofemoral venous obstruction found "excellent" outcomes. Several useful techniques and pearls for improved outcomes are reported in the January edition of the Journal of Vascular Surgery: Venous and Lymphatic Disorders. Placement...
Merit Medical Systems, Inc. has announced that it has acquired substantially all of the assets of Vascular Insights, LLC, based in Quincy, USA. Vascular Insights’ primary assets are the ClariVein IC and ClariVein OC specialty infusion and occlusion catheter...
The study data were delivered in two presentations at VEITHsymposium (13–17 November, New York, USA) by Mark Adelman (NYU Langone Hosptial, New York, USA) and Kathleen Gibson (Lake Washington Vascular Surgeons, Bellevue, USA). They explained that incompetent perforator veins are...
 An analysis of ATTRACT has recently been published in the journal Circulation, in which the authors examine the effect of pharmacomechanical catheter-directed therapy (PCDT) in ATTRACT patients with iliofemoral deep vein thrombosis (DVT). As a result of this, Venous News spoke to...
 Venous News arranged a roundtable with Sophie Renton (London, UK), Bruce Campbell (Exeter, UK) and Manj Gohel (Cambridge, UK), who called for more high quality, medium-to-long-term evidence to support the growing use of minimally invasive, but expensive, interventions for deep...
The members of the American College of Phlebology (ACP) have voted to change their name to the American Vein and Lymphatic Society (AVLS). The name change is a part of the Society’s mission and vision to provide advocacy efforts,...
A new study, recently published online in the journal Circulation, reports on outcomes from a subgroup of 391 patients with acute iliofemoral deep venous thrombosis (DVT) in whom pharmacomechanical catheter-directed thrombolysis (PCDT) was evaluated within the ATTRACT trial. The authors,...
 Kathleen Gibson (Bellevue, USA), one of the principal investigators of the SeCure trial, presented its results at the ACP 2018 annual congress. “More than closure rates, it is the quality of life findings from this trial that are important...
Inari Medical has announced the enrolment of the first patient in the FlowTriever All-Comer Registry for Patient Safety and Hemodynamics (FLASH) using the company’s FlowTriever System for the treatment of pulmonary embolism (PE). FLASH is a 500-patient prospective, multicentre registry...
Results from the Phase 3 CASSINI study contributes new data on the use of oral anticoagulant rivaroxaban (brand name Xarelto, Johnson & Johnson) in the management and prevention of venous thromboembolism (VTE) in high-risk patients with cancer. The composite...
The world’s first bioconvertible IVC filter commercially offered in the USA (Sentry; from BTG) has been successfully implanted into the first patients outside of a clinical trial. The Sentry filter is designed to provide protection from pulmonary embolism for the...
In this issue: Strategies needed to address radiation exposures during venous procedures Nationwide study finds no significant difference between rivaroxaban and apixaban for VTE patients Profile: Ramesh Tripathi Una adderley: Choosing the right compression Alison Hopkins: Changing the narrative...
In this issue: Strategies needed to address radiation exposures during venous procedures Nationwide study finds no significant difference between rivaroxaban and apixaban for VTE patients Profile: Ramesh Tripathi Una adderley: Choosing the right compression Alison Hopkins: Changing the narrative...
The US FDA has announced plans to modernise its 510(k) clearance programme for approving medical devices for the US market. Data show that about 20% of current 510(k) devices are approved on trials that compare novel devices to predicate...

Ramesh Tripathi

Having worked as a vascular surgeon and venous specialist in several different countries and continents, Ramesh Tripathi has a wide-ranging experience and storied career. He tells Venous News about his current areas of research, his opinion of the most important...
Boston Scientific has announced it has reached an agreement on the terms of a recommended offer to acquire BTG, a company headquartered in the United Kingdom, which develops and commercialises products used in minimally-invasive procedures targeting cancer and vascular...
Two-year results for the SENTRY trial were presented at the Vascular Interventional Advances conference (VIVA; 5–8 November, Las Vegas, USA). The prospective, multicentre trial of the Sentry (BTG), a bioconvertible IVC filter, found that in addition to providing protection...
The 12-month results from the VERNACULAR trial have shown that the Venovo venous stent (BD Interventional) is successful when deployed in obstructive iliac and femoral lesions with a primary patency rate of 88.3%, a low reintervention rate of 7.4%,...
BTG has announced that the first EKOS Control Unit 4.0 have been shipped from BTG’s facility in Bothell (Washington, USA) to Europe, where full commercial launch will begin. New features of the EKOS CU 4.0 include an interactive colour...
There is a robust evidence base to support the use of compression therapy for healing venous leg ulceration and for preventing ulcer recurrence. The most recent version of the Cochrane Review1 on the effectiveness of compression and the relative effectiveness of different...
Theraclion has announced that Alfred Obermayer, principal investigator of the varicose vein treatment clinical trial in Austria, presented preliminary results at the Congress of the German Society of Phlebology in Bielefeld, attended by around 1,200 participants. The study aims...
At the Royal Society of Medicine (RSM) Venous Forum meeting (25–26 June, London, UK), Alison Hopkins was asked to speak about managing painful leg ulcers. She took the opportunity to focus on the need to improve the art of...
A recent Danish study, examining a nationwide cohort of 8,187 patients with venous thromboembolism (VTE) treated with one of two new oral anticoagulant therapies, reports no significant differences between the drugs in risk of all-cause mortality, recurrent VTE or...
Research presented at the European Society for Vascular Surgery’s annual meeting (ESVS; 25–28 September, Valencia, Spain) has shone a light on the potentially high cumulative radiation exposure associated with certain venous procedures. Addressing the issue, Stephen Black (Guy’s and...
In this issue: "Crystal clear" evidence that higher compression reduces ulcer recurrence New intravascular ultrasound-based scoring system may predict stent failure Managing superficial vein thrombosis Profile: Kathleen Gibson  
This article is an advertorial sponsored by plus medica The blueflow Venous Stent developed by plus medica GmbH & Co. KG received CE mark in early 2018, and has now been used in 60 patients at two centres in Europe....
A recent study which set out to investigate the usefulness of duplex ultrasound in monitoring stent changes over time, concludes that stent occlusion is related to the reduction of stent lumen over time—rather than the percent of the stenosis. Investigators...
Peripartum women with deep vein thrombosis (DVT) treated with catheter-directed thrombolysis and venous stenting had significantly increased rates of reintervention and loss of stent patency compared with non-pregnant women treated at the same centre. Katalin Lestak (St Thomas’ Hospital, London, UK) presented...
A report of an eight-year experience using diode laser for the treatment of congenital diffuse venous malformations, has shown the modality to be effective and safe with a low number of complications. The experience from the Vascular Anomalies Unit in...
A study presented at the European Society for Vascular Surgery’s annual meeting (ESVS; 25–28 September, Valencia, Spain) has concluded that mechanochemical ablation with concomitant ambulatory phlebectomy (MOCAP) results in greater early improvement in quality of life and significant reduction...

Kathleen Gibson

An accomplished vascular surgeon and prominent clinical researcher in the venous field, Kathleen Gibson (Lake Washington Vascular Surgeons, Bellevue, USA) plays an active role in a range of venous and vascular societies, and is currently involved in developing standardisation...

Venous News 7 – September 2018

In this issue: "Crystal clear" evidence that higher compression reduces ulcer recurrence New intravascular ultrasound-based scoring system may predict stent failure Managing superficial vein thrombosis Profile: Kathleen Gibson  
Anna Louise Pouncey revealed at the European Venous Forum annual meeting (EVF; 28–30 June, Athens, Greece) the findings of the GSTT venous team (Guy’s and St Thomas’ NHS Foundation Trust & Kings College London, London, UK) that early use...
Superficial vein thrombosis is not a rare disease, with an incidence of 0.64 in 1,000 annually.1 The POST, OPTIMEV and STEPH studies have shown that superficial vein thrombosis may be associated with a considerable risk of concomitant deep vein...
The utility of combining patient- and physician-reported scores to stratify disease severity and treatment rationale in patients with varicose veins has been highlighted in a recent study by Lowell Kabnick, Thomas Wakefield, Mikel Sadek, Jose Almeida and Glenn Jacobowitz,...

BTG acquires Novate Medical

BTG has announced it has acquired Novate Medical, a medical device company focused on the prevention of pulmonary embolism in patients at high risk of venous thromboembolic events. Novate has developed Sentry, the first bioconvertible inferior vena cava filter, which...
Mermaid Medical Group, a privately-owned international provider of minimally invasive medical devices, acknowledged a product line addition to its vascular business. As part of its strategic focus for expanding their vascular product portfolio, Mermaid Medical Group announced the acquisition...
Alex C Spyropoulos, from Feinstein Institute for Medical Research (New York, USA), has presented an anticoagulant treatment strategy to reduce non-fatal blood clots and pulmonary embolism in acutely-ill hospitalised patients, according to clinical findings published in The New England...
One of the first randomised controlled trials comparing two therapeutic regimes—surgery and foam sclerotherapy—in patients with anterior accessory saphenous vein (AASV) varicosis, has found that surgery can outperform foam sclerotherapy in terms of duplex sonographic recurrence after one year....
To accompany the growing importance of intravascular ultrasound (IVUS) as an adjuvant diagnostic tool when treating deep venous disease, a study sought to create an IVUS-based scoring system able to predict venous stent failure in the treatment of May-Thurner...
Hancock Jaffe Laboratories, a company specialising in bioprosthetic medical devices for treating cardiac and vascular diseases, has received approval for the first-in-man testing of its VenoValve bioprosthetic venous valve device from the Medical Research Committee at Fundación Santa Fe...
According to Fedor Lurie (Jobst Vascular Institute, Toledo, USA), who presented at the European Venous Forum Annual Meeting (EVF; 28–30 June, Athens, Greece), patients with a high probability of iliofemoral deep vein thrombosis (DVT) are not diagnosed early enough...
A first prototype of a novel endovenous therapy technology (SnakeBack, LSO Medical) integrated with a laser ablation platform was revealed earlier this year at the Charing Cross Symposium (CX; 24-27 April, London, UK) by Philippe Rochon, president of LSO...
Boston Scientific has signed an agreement to acquire Veniti, a privately-held company in Fremont, USA which developed and commercialised the Vici venous stent system for treating venous obstructive disease. Boston Scientific has been an investor in Veniti since 2016 and...
NexGen Medical Systems, Inc., a US medical device company, has announced the successful completion of the first human use of their XCOIL large vessel (18mm) thrombectomy system for the treatment of deep vein thrombosis (DVT). The new device, an expansion...
A new analysis has identified patient populations with cancer-associated venous thromboembolism (VTE) who could benefit from treatment with oral anticoagulant edoxaban, taken once daily. Daiichi Sankyo has announced the publication of a new analysis, focusing on the clinical presentation, course...
A Cambridge study has found that most inpatients with leg ulcers were not referred to a vascular surgery team, indicating a need to improve pathways of care for inpatients with leg ulcerations. The results of the study conducted at Addenbrooke’s...
Venclose has announced the closing of an oversubscribed Series B round of financing from new and existing investors. Proceeds from the financing will be used to support new product development, expansion of manufacturing capabilities and general corporate purposes. The company...
EchoNous Vein (EchoNous), an ultrasound-based tool designed specifically for nurses to improve peripheral IV catheter placements, has received US Food and Drug Administration (FDA) approval. A company release explains that EchoNous Vein provides immediate, clear images at depths from 1–5cm...

Alun Davies

Alun Davies is a Welsh-born leading expert in the venous field, one of the Editors-in-Chief of Venous News, and currently in the spotlight as chief investigator of the EVRA ulcer trial. In this profile, Davies talks about the implications...
Highlights: Landmark EVRA trial provides first Level 1 evidence for early venous ablation Ultrasound-guided foam sclerotherapy of small saphenous vein as effective as endovenous laser ablation for venous clinical severity score and quality of life at one year Rick...
Highlights: Landmark EVRA trial provides first Level 1 evidence for early venous ablation Ultrasound-guided foam sclerotherapy of small saphenous vein as effective as endovenous laser ablation for venous clinical severity score and quality of life at one year Rick...
An analysis of post-thrombotic disease patients who received a nitinol stent has found that ultrasound surveillance should occur at frequent intervals up to two weeks post-procedure to predict risk of re-intervention. The results of the study were presented at the...
A new randomised controlled trial evaluated the preventative effect of compression stockings during pregnancy on the incidence of varicose veins as well as venous thromboembolism, with results suggesting that women with no venous disease using compression stocking during pregnancy...
BTG has announced a strategic partnership with the PERT Consortium to advance the science of pulmonary embolism treatment and promote the implementation of PERT programmes across the USA. The partnership was announced at the annual PERT Consortium Meeting (22–23...
The annual census of UK consultants and higher speciality trainees—Focus on Physicians 2017–18—indicates that more than half of all consultants and two thirds of trainees reported frequent gaps in trainees’ rotas, with one in five respondents saying these are...
The one-year results of the ACCESS PTS trial have shown that EKOS therapy (BTG) statistically improves post-thrombotic syndrome scores and sequelae as well as quality of life outcomes. Presenting the data at the Charing Cross Symposium (24–27 April, London,...
Cees Wittens writes for Venous News about the current state of deep venous obstruction interventions, what we might expect in the near future, and what is needed in terms of new technology, strategy and policy in 2018. In general, everybody...
Treatment of patients with pelvic venous disorders is a “controversial topic,” Kathleen Gibson (Lake Washington Vascular Surgeons, Bellevue, USA) said at the Charing Cross Symposium (CX; 24–27 April, London, UK), as there is “no consensus on the best mode...